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Article

Association between rs2275913 single-nucleotide polymorphism of the interleukin-17A gene and perioperative analgesic use in cosmetic orthognathic surgery.

Neuropsychopharmacology reports - 1 Jun 2018

Ohka Seii, Nishizawa Daisuke, Hasegawa Junko, Takahashi Kaori, Nakayama Kyoko, Ebata Yuko, Fukuda Ken-Ichi, Ikeda Kazutaka

Abstract excerpt

AIM: Interleukin-17A (IL-17A) plays an essential role in tissue inflammation by inducing proinflammatory cytokine and chemokine production and is related to innate immune reactions. IL-17A also contributes to neuroinflammation, neuropathic pain, and mechanical hypersensitivity after peripheral nerve injury in rodents. To clarify the contribution of IL-17A to pain-related phenotypes in humans, we investigated the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30106258
DOI: 10.1002/npr2.12010
PMCID: PMC7292295

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