Article
Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain.
Anesthesiology - 1 Mar 2018
Tian Yuanyuan, Liu Xiaodong, Jia Mingzhong, Yu Hui, Lichtner Peter, Shi Yujian, Meng Zhaoyu, Kou Shanglong, Ho Idy H T, Jia Bo, Cheng Benny C P, Lam Carmen K M, Tsang Sharon, Wong Sunny H, Yu Jun, Cheng Christopher H K, Gin Tony, Wu William K K, Chen Zheyu, Chan Matthew T V
Abstract excerpt
BACKGROUND: The purpose of this study was to evaluate the association between single-nucleotide polymorphisms and chronic postsurgical pain. METHODS: Using GoldenGate genotyping assays, we genotyped 638 polymorphisms within 54 pain-related genes in 1,152 surgical patients who were enrolled in our Persistent Pain after Surgery Study. Patients were contacted by phone to determine whether they had chronic...
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