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Article

Prediction formulas for individual opioid analgesic requirements based on genetic polymorphism analyses.

PloS one - 1 Jan 2015

Yoshida Kaori, Nishizawa Daisuke, Ichinomiya Takashi, Ichinohe Tatsuya, Hayashida Masakazu, Fukuda Ken-ichi, Ikeda Kazutaka

Abstract excerpt

BACKGROUND: The analgesic efficacy of opioids is well known to vary widely among individuals, and various factors related to individual differences in opioid sensitivity have been identified. However, a prediction model to calculate appropriate opioid analgesic requirements has not yet been established. The present study sought to construct prediction formulas for individual opioid analgesic requirements based on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25615449
DOI: 10.1371/journal.pone.0116885
PMCID: PMC4304713

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PPL

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