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Article

JUM is a computational method for comprehensive annotation-free analysis of alternative pre-mRNA splicing patterns.

Proceedings of the National Academy of Sciences of the United States of America - 28 Aug 2018

Wang Qingqing, Rio Donald C

Abstract excerpt

Alternative pre-mRNA splicing (AS) greatly diversifies metazoan transcriptomes and proteomes and is crucial for gene regulation. Current computational analysis methods of AS from Illumina RNA-sequencing data rely on preannotated libraries of known spliced transcripts, which hinders AS analysis with poorly annotated genomes and can further mask unknown AS patterns. To address this critical bioinformatics problem,...

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Identifiers

PMID: 30104386
DOI: 10.1073/pnas.1806018115
PMCID: PMC6126775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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