Article
Particles in exhaled air (PExA): non-invasive phenotyping of small airways disease in adult asthma.
Journal of breath research - 14 Sept 2018
Soares Marcia, Mirgorodskaya Ekaterina, Koca Hatice, Viklund Emilia, Richardson Matthew, Gustafsson Per, Olin Anna-Carin, Siddiqui Salman
Abstract excerpt
RATIONALE: Asthma is often characterised by inflammation, damage and dysfunction of the small airways, but no standardised biomarkers are available. OBJECTIVES: Using a novel approach-particles in exhaled air (PExA)-we sought to (a) sample and analyse abundant protein biomarkers: surfactant protein A (SPA) and albumin in adult asthmatic and healthy patients and (b) relate protein concentrations with physiological...
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