Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers.

doi:10.1007/s11306-018-1412-2

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Article

Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers.

Metabolomics : Official journal of the Metabolomic Society - 17 Sept 2018

Brandsma Joost, Goss Victoria M, Yang Xian, Bakke Per S, Caruso Massimo, Chanez Pascal, Dahlén Sven-Erik, Fowler Stephen J, Horvath Ildiko, Krug Norbert, Montuschi Paolo, Sanak Marek, Sandström Thomas, Shaw Dominick E, Chung Kian Fan, Singer Florian, Fleming Louise J, Sousa Ana R, Pandis Ioannis, Bansal Aruna T, Sterk Peter J, Djukanović Ratko, Postle Anthony D

Abstract excerpt

BACKGROUND: Lung epithelial lining fluid (ELF)-sampled through sputum induction-is a medium rich in cells, proteins and lipids. However, despite its key role in maintaining lung function, homeostasis and defences, the composition and biology of ELF, especially in respect of lipids, remain incompletely understood. OBJECTIVES: To characterise the induced sputum lipidome of healthy adult individuals, and to examine...

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PMID: 30830396
DOI: 10.1007/s11306-018-1412-2
PMCID: PMC6153688

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