Article

Quantitative CT of Normal Lung Parenchyma and Small Airways Disease Topologies are Associated With COPD Severity and Progression

2023-06-05

Abstract excerpt

<h4>Objectives</h4> Small airways disease (SAD) is a major cause of airflow obstruction in COPD patients, and has been identified as a precursor to emphysema. Although the amount of SAD in the lungs can be quantified using our Parametric Response Mapping (PRM) approach, the full breadth of this readout as a measure of emphysema and COPD progression has yet to be explored. We evaluated topological features of PRM-d...

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Literature Corpus work: 1f471646-9051-5959-8c88-c41dd1268c51
DOI: 10.1101/2023.05.26.23290532

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