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Article

Heterogeneity and longevity of antibody memory to viruses and vaccines

10 Aug 2018

Abstract excerpt

Determining the duration of protective immunity requires quantifying the magnitude and rate of loss of antibodies to different virus and vaccine antigens. A key complication is heterogeneity in both the magnitude and decay rate of responses of different individuals to a given vaccine, as well as of a given individual to different vaccines. We analyzed longitudinal data on antibody titers in 45 individuals to...

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PMID: 30096134
DOI: 10.1371/journal.pbio.2006601

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