Article
The GTP-binding protein Rho1p is required for cell cycle progression and polarization of the yeast cell.
The Journal of cell biology - 26 Jul 1999
Drgonová J, Drgon T, Roh D H, Cabib E
Abstract excerpt
Previous work showed that the GTP-binding protein Rho1p is required in the yeast, Saccharomyces cerevisiae, for activation of protein kinase C (Pkc1p) and for activity and regulation of beta(1-->3)glucan synthase. Here we demonstrate a hitherto unknown function of Rho1p required for cell cycle progression and cell polarization. Cells of mutant rho1(E45I) in the G1 stage of the cell cycle did not bud at 37 degrees...
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