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Article

The prognostic effect of single and multiple cancer-related somatic mutations in resected non-small-cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2018

Jao Kevin, Tomasini Pascale, Kamel-Reid Suzanne, Korpanty Gregorz J, Mascaux Céline, Sakashita Shingo, Labbé Catherine, Leighl Natasha B, Liu Geoffrey, Feld Ronald, Bradbury Penelope A, Hwang David M, Pintilie Melania, Tsao Ming-Sound, Shepherd Frances A

Abstract excerpt

INTRODUCTION: Somatic mutations are becoming increasingly important biomarkers for treatment selection and outcome in patients with non-small-cell lung cancer (NSCLC). The role of multiple somatic mutations in early-stage NSCLC is unclear. METHODS: Tissue from 214 patients with resected NSCLC at the Princess Margaret Cancer Centre was analyzed by next-generation sequencing by Mi-SEQ or Sequenom multiplex...

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Identifiers

PMID: 30089591
DOI: 10.1016/j.lungcan.2018.06.023

Genes

EGFR
KRAS

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