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Clinicopathological significance of mutation profile detected by next generation sequencing in different metastatic organs of non-small cell lung cancers.

Pathology, research and practice - 1 Aug 2024

Akın Dilara, Kahraman Çeti N Nesibe, Erdoğdu İbrahim Halil, Öztürk Hakan, Meteoğlu İbrahim

Abstract excerpt

BACKGROUND: The primary tumor and it's metastases show heterogeneity in molecular studies for targeted therapies in Non-Small Cell Lung Cancer(NSCLC), the leading cause of cancer-related deaths worldwide. The study aimed to identify somatic mutations in biopsies from NSCLC patients' metastatic organs using Next-Generation Sequencing(NGS) and examine their association with clinicopathological parameters. MATERIALS...

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Aged
Biomarkers, Tumor
Brain Neoplasms
Carcinoma, Non-Small-Cell Lung
DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

High-Throughput Nucleotide Sequencing

Lymphatic Metastasis

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PMID: 39013258
DOI: 10.1016/j.prp.2024.155463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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