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Article

EGFR-mutant lung adenocarcinoma harboring co-mutational tumor suppressor genes predicts poor prognosis.

Journal of cancer research and clinical oncology - 1 Jul 2020

Zhao Yue, Pan Yunjian, Cheng Chao, Zheng Difan, Zhang Yang, Gao Zhendong, Fu Fangqiu, Li Hang, Zheng Shanbo, Zhuge Lingdun, Mao Hengyu, Kuang Muyu, Tao Xiaoting, Peng Yizhou, Hu Hong, Xiang Jiaqing, Li Yuan, Sun Yihua, Chen Haiquan

Abstract excerpt

INTRODUCTION: EGFR mutations occur most frequently in patients with lung adenocarcinoma in East Asia. However, the prognostic and therapeutic impact of co-mutational status of EGFR and tumor suppressor genes is not fully understood. This study aims to provide a deeper understanding of lung adenocarcinoma patients with co-mutation of EGFR and tumor suppressor genes. METHODS: From November 2009 to May 2016, 675...

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PMID: 32361787
DOI: 10.1007/s00432-020-03237-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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