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Article

Prognostic and predictive effects of TP53 co-mutation in patients with EGFR-mutated non-small cell lung cancer (NSCLC).

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2017

Labbé Catherine, Cabanero Michael, Korpanty Grzegorz J, Tomasini Pascale, Doherty Mark K, Mascaux Céline, Jao Kevin, Pitcher Bethany, Wang Rick, Pintilie Melania, Leighl Natasha B, Feld Ronald, Liu Geoffrey, Bradbury Penelope Ann, Kamel-Reid Suzanne, Tsao Ming-Sound, Shepherd Frances A

Abstract excerpt

INTRODUCTION: TP53 mutations are common in non-small cell lung cancer (NSCLC) and have been reported as prognostic of poor outcome. The impact of TP53 co-mutations in epidermal growth factor receptor (EGFR)-mutated NSCLC is unclear. MATERIALS AND METHODS: Tissue from 105 patients with EGFR-mutated NSCLC at Princess Margaret Cancer Centre was analyzed by next-generation or Sanger sequencing to determine TP53...

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Identifiers

PMID: 28838393
DOI: 10.1016/j.lungcan.2017.06.014

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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