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Article

The long tail of molecular alterations in non-small cell lung cancer: a single-institution experience of next-generation sequencing in clinical molecular diagnostics.

Journal of clinical pathology - 1 Sept 2018

Fumagalli Caterina, Vacirca Davide, Rappa Alessandra, Passaro Antonio, Guarize Juliana, Rafaniello Raviele Paola, de Marinis Filippo, Spaggiari Lorenzo, Casadio Chiara, Viale Giuseppe, Barberis Massimo, Guerini-Rocco Elena

Abstract excerpt

BACKGROUND: Molecular profiling of advanced non-small cell lung cancers (NSCLC) is essential to identify patients who may benefit from targeted treatments. In the last years, the number of potentially actionable molecular alterations has rapidly increased. Next-generation sequencing allows for the analysis of multiple genes simultaneously. AIMS: To evaluate the feasibility and the throughput of next-generation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29535211
DOI: 10.1136/jclinpath-2018-205032

Genes

EGFR
KRAS
FGFR1
MET
STK11

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