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Article

The New Genetic Landscape of Cushing’s Disease: Deubiquitinases in the Spotlight

8 Nov 2019

Abstract excerpt

Cushing's disease (CD) is a rare condition caused by adrenocorticotropic hormone (ACTH)-producing adenomas of the pituitary, which lead to hypercortisolism that is associated with high morbidity and mortality. Treatment options in case of persistent or recurrent disease are limited, but new insights into the pathogenesis of CD are raising hope for new therapeutic avenues. Here, we have performed a meta-analysis...

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PMID: 31717455
DOI: 10.3390/cancers11111761

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