Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical Spectrum of USP8 Pathogenic Variants in Cushing's Disease

2 Nov 2023

Abstract excerpt

Cushing's disease (CD) is a life-threatening condition with a challenging diagnostic process and scarce treatment options. CD is caused by usually benign adrenocorticotrophic hormone (ACTH)-secreting pituitary neuroendocrine tumors (PitNETs), known as corticotropinomas. These tumors are predominantly of sporadic origin, and usually derive from the monoclonal expansion of a mutated cell. Somatic activating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal and Paraganglionic Tumors
Share to Adrenal Hormones and Disorders
Share to Pituitary Gland Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37925320
DOI: 10.1016/j.arcmed.2023.102899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical Spectrum of USP8 Pathogenic Variants in Cushing's DiseasePMID 37925320Read ↗

Decoding the genetic basis of Cushing's disease: USP8 in the spotlight.Semantic proximity Read ↗

Recurrent gain-of-function USP8 mutations in Cushing's diseaseSemantic proximity Read ↗

PATHOGENESIS OF CUSHING DISEASE: AN UPDATE ON THE GENETICS OF CORTICOTROPINOMAS.Semantic proximity Read ↗

The New Genetic Landscape of Cushing’s Disease: Deubiquitinases in the SpotlightSemantic proximity Read ↗

Genetics of Cushing's disease.Semantic proximity Read ↗

Driver mutations in USP8 wild-type Cushing’s diseaseSemantic proximity Read ↗

Identification of recurrent USP48 and BRAF mutations in Cushing's disease.Semantic proximity Read ↗

Relevance of mutations in protein deubiquitinases genes and TP53 in corticotroph pituitary tumors.Semantic proximity Read ↗

Genetic Profiling of a Cohort of Italian Patients with ACTH-Secreting Pituitary Tumors and Characterization of a Novel USP8 Gene VariantSemantic proximity Read ↗

Identification of a novel RASD1 somatic mutation in a USP8-mutated corticotroph adenoma.Semantic proximity Read ↗

Germline USP8 Mutation Associated With Pediatric Cushing Disease and Other Clinical Features: A New SyndromeSemantic proximity Read ↗

Genetics of Cushing's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.