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Article

Genetics of Cushing's disease.

Clinical endocrinology - 1 Jan 2018

Albani Adriana, Theodoropoulou Marily, Reincke Martin

Abstract excerpt

Cushing's disease (CD) is a rare disabling condition caused by Adrenocorticotropic hormone (ACTH)-secreting adenomas of the pituitary. The majority of corticotropic adenomas are monoclonal and occur sporadically. Only rarely does CD arise in the context of genetic familial syndromes. Targeted sequencing of oncogenes and tumour suppressor genes commonly mutated in other tumours did not identify recurrent...

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Source

Identifiers

PMID: 28850717
DOI: 10.1111/cen.13457

Genes

USP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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