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Article

Clinical importance of different calreticulin gene mutation types in wild-type JAK2 essential thrombocythemia and myelofibrosis patients

11 Jul 2014

Abstract excerpt

The Janus kinase 2 (JAK2) V617F mutation (JAK2 V617F), JAK2 exon 12 mutations and myeloproliferative leukemia virus oncogene W515L/K mutation (MPL W515L/K) have become three major molecular diagnosis criteria for myeloproliferative neoplasms (MPNs) including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) from 2005. 1 However, diagnosing MPNs with non-mutated JAK2 and MPL...

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Identifiers

PMID: 25015940
DOI: 10.3324/haematol.2014.109199

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