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Article

Lack of association between cytotoxic T-lymphocyte antigen-4 -318C/T polymorphism and cancer risk: a meta-analysis of case-control studies.

Technology in cancer research & treatment - 1 Dec 2013

Xia Wei, Shi Rong, Zheng Wen-Ling, Ma Wen-Li

Abstract excerpt

Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is important for the down regulation of T-cell activation. Number of studies assessed the association between CTLA-4 -318C/T polymorphisms and cancer in different populations. However, the studies have provided conflicting results. We performed a meta-analysis to examine the association between CTLA-4 -318C/T polymorphisms and cancer susceptibility. Eligible studies were...

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Identifiers

PMID: 23745791
DOI: 10.7785/tcrt.2012.500350

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