Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevention of Lymphocyte Neurotoxic Effects by microRNA Delivery.

MicroRNA (Shariqah, United Arab Emirates) - 1 Jan 2014

Pulliero Alessandra, Marengo Barbara, Fenoglio Daniela, Parodi Alessia, Cereda Cristina, Domenicotti Cinzia, Orcesi Simona, Galli Jessica, Olivieri Ivana, Filaci Gilberto, Balottin Umberto, Fazzi Elisa, Izzotti Alberto

Abstract excerpt

Aicardi Goutieres Syndrome (AGS) is characterized by mutations occurring in genes encoding RNAses. AGS mutations silence intracellular RNases resulting in an intracellular overload of short RNAs arresting the physiological production of microRNA required for brain development. MiR-219 is typically down-regulated in Aicardi Goutieres Syn-drome (AGS). The goal of this study is to investigate miR-219 role in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytes
Share to Autoimmune Diseases of the Nervous System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coculture Techniques

Share to Interferon-alpha

Share to Lymphocytes

Share to Necrosis

Share to Nervous System Malformations

Share to Ribonucleases

Source

Identifiers

PMID: 25069442
DOI: 10.2174/22115366113029990010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevention of Lymphocyte Neurotoxic Effects by microRNA Delivery.PMID 25069442Read ↗

Astrocytes, an active player in Aicardi-Goutières syndrome.Semantic proximity Read ↗

Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFN-stimulated gene response and cytokine release.Semantic proximity Read ↗

The prototypical interferonopathy: Aicardi-Goutières syndrome from bedside to bench.Semantic proximity Read ↗

Type I interferon pathway in CNS homeostasis and neurological disordersSemantic proximity Read ↗

MicroRNAs: protective regulators for neuron growth and developmentSemantic proximity Read ↗

IL28B, IL29 and micro-RNA 548 in subacute sclerosing panencephalitis as a rare disease.Semantic proximity Read ↗

The mmu_circ_0000335 inhibits M1 microglial-induced hippocampal neuronal apoptosis via the miR-19b-3p/SOCS1 axis in a mouse epilepsy modelSemantic proximity Read ↗

Interferon-related transcriptome alterations in the cerebrospinal fluid cells of Aicardi-Goutières patients.Semantic proximity Read ↗

BM-MSCs ameliorate experimental autoimmune encephalomyelitis via modifying the expression of miR-193, miR-146a, miR-155, miR-21 and miR-326Semantic proximity Read ↗

IL-17 Exerts Anti-Apoptotic Effect via miR-155-5p Downregulation in Experimental Autoimmune EncephalomyelitisSemantic proximity Read ↗

Antagonistic activity of AEA on TAT treated Human Astrocytes identify Inflammaging pathwaysSemantic proximity Read ↗

Treatments in Aicardi–Goutières syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.