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Autophagy and Rheumatoid Arthritis: Current Knowledges and Future Perspectives

18 Jul 2018

Abstract excerpt

Autophagy is a degradation mechanism by which cells recycle cytoplasmic components to generate energy. By influencing lymphocyte development, survival, and proliferation, autophagy regulates the immune responses against self and non-self antigens. Deregulation of autophagic pathway has recently been implicated in the pathogenesis of several autoimmune diseases, including rheumatoid arthritis (RA). Indeed,...

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PMID: 30072986
DOI: 10.3389/fimmu.2018.01577

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