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Pharmacological insights into autophagy modulation in autoimmune diseases

23 Mar 2021

Abstract excerpt

As a cellular bulk degradation and survival mechanism, autophagy is implicated in diverse biological processes. Genome-wide association studies have revealed the link between autophagy gene polymorphisms and susceptibility of autoimmune diseases including systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD), indicating that autophagy dysregulation may be involved in the development of...

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PMID: 34900523
DOI: 10.1016/j.apsb.2021.03.026

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