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Article

miR‑92b promotes autophagy and suppresses viability and invasion in breast cancer by targeting EZH2

18 Jul 2018

Abstract excerpt

MicroRNAs (miRs) are a small non-coding RNA family with a length of 18-22 nucleotides. They are able to regulate gene expression by either triggering target messenger RNA degradation or by inhibiting mRNA translation. Enhancer of zeste homolog 2 (EZH2) is the core enzymatic subunit of polycomb repressor complex 2 and is responsible for the trimethylation of histone 3 on lysine 27 (H3K27me3); it is also able to...

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PMID: 30066891
DOI: 10.3892/ijo.2018.4486

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