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Autophagy, Cell Viability, and Chemoresistance Are Regulated By miR-489 in Breast Cancer

21 May 2018

Abstract excerpt

Abstract It is postulated that the complexity and heterogeneity in cancer may hinder most efforts that target a single pathway. Thus, discovery of novel therapeutic agents targeting multiple pathways, such as miRNAs, holds promise for future cancer therapy. One such miRNA, miR-489, is downregulated in a majority of breast cancer cells and several drug-resistant breast cancer cell lines, but its role and...

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PMID: 29784669
DOI: 10.1158/1541-7786.mcr-17-0634

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