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Article

Bacterial developmental checkpoint that directly monitors cell surface morphogenesis.

Developmental cell - 7 Feb 2022

Delerue Thomas, Anantharaman Vivek, Gilmore Michael C, Popham David L, Cava Felipe, Aravind L, Ramamurthi Kumaran S

Abstract excerpt

Bacillus subtilis spores are encased in two concentric shells: an outer proteinaceous "coat" and an inner peptidoglycan "cortex," separated by a membrane. Cortex assembly depends on coat assembly initiation, but how cells achieve this coordination across the membrane is unclear. Here, we report that the protein SpoVID monitors the polymerization state of the coat basement layer via an extension to a functional...

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Identifiers

PMID: 35065768
DOI: 10.1016/j.devcel.2021.12.021
PMCID: PMC8991396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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