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Article

BMP1 5'UTR + 104 T/C gene variation: can be a predictive marker for serum HDL and apoprotein A1 levels in male patients with coronary heart disease.

Molecular biology reports - 1 Oct 2018

Akadam-Teker Basak, Ozkara Gulcin, Kurnaz-Gomleksiz Ozlem, Bugra Zehra, Teker Erhan, Ozturk Oguz, Yilmaz-Aydogan Hulya

Abstract excerpt

Apolipoprotein A1 (Apo A1), the major protein of HDL, is secreted as a proprotein and then is cleaved by C-terminal procollagen endoproteinase/bone morphogenetic protein-1 (BMP1). BMP1 stimulates the conversion of newly secreted proapo A1 to its phospholipid-binding form. Therefore, genetic variations of BMP1 gene may affect serum ApoA1 and HDL levels. We aimed to investigate the effects of the functional...

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Identifiers

PMID: 30062502
DOI: 10.1007/s11033-018-4283-8

Genes

BMP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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