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Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1

24 Feb 2009

Abstract excerpt

Given the increased prevalence of cardiovascular disease in the world, the search for genetic variations controlling the levels of risk factors associated with the development of the disease continues. Multiple genetic association studies suggest the involvement of procollagen C-proteinase enhancer-2 (PCPE2) in modulating HDL-C levels. Therefore biochemical and mechanistic studies were undertaken to determine...

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PMID: 19237735
DOI: 10.1194/jlr.m900034-jlr200

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