Article
Common genetic variants of the BMP4, BMPR1A, BMPR1B, and ACVR1 genes, left ventricular mass, and other parameters of the heart in newborns.
Genetic testing and molecular biomarkers - 1 Nov 2012
Gorący Iwona, Safranow Krzysztof, Dawid Grażyna, Skonieczna-Żydecka Karolina, Kaczmarczyk Mariusz, Gorący Jarosław, Loniewska Beata, Ciechanowicz Andrzej
Abstract excerpt
The members of the family of bone morphogenetic proteins (BMPs) are important regulators in cardiac development. The present study was designed to evaluate the effect of common genetic variants of BMP-4 and its receptors BMPR1A, BMPR1B, and ACVR1 on left ventricular mass (LVM) and other parameters of the heart and blood pressure in newborns. The study included 210 healthy newborns. Two-dimensional M-mode...
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