Article
The PHO pathway regulates white-opaque switching and sexual mating in the human fungal pathogen Candida albicans.
Current genetics - 1 Dec 2020
Zheng Qiushi, Guan Guobo, Cao Chengjun, Li Qi, Huang Guanghua
Abstract excerpt
The opportunistic fungal pathogen Candida albicans is able to switch among several morphological phenotypes in response to environmental changes. White-opaque transition is a typical phenotypic switching system involved in the regulation of pathogenesis and sexual reproduction in C. albicans. Under regular laboratory culture conditions, to undergo white-to-opaque switching, cells must first undergo homozygosis at...
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