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Article

Using Stepwise Pharmacogenomics and Proteomics to Predict Hepatitis C Treatment Response in Difficult to Treat Patient Populations.

Proteomics. Clinical applications - 1 May 2019

Naggie Susanna, Clement Meredith, Lusk Sam, Osinusi Anu, Himmel Tiffany, Lucas Joseph E, Thompson Will J, Dubois Laura, Moseley M Arthur, Clark Paul J, Kottilil Shyam, Patel Keyur

Abstract excerpt

PURPOSE: In the interferon era of hepatitis C virus (HCV) therapies, genotype/subtype, cirrhosis, prior treatment failure, sex, and race predicted relapse. Our objective is to validate a targeted proteomics platform of 17 peptides to predict sustained virologic response (SVR). EXPERIMENTAL DESIGN: Stored plasma from three, open-label, trials of HIV/HCV-coinfected subjects receiving interferon-containing regimens...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30058111
DOI: 10.1002/prca.201800006
PMCID: PMC6353701

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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