Article
Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C.
PloS one - 1 Jan 2011
Cyr Derek D, Lucas Joseph E, Thompson J Will, Patel Keyur, Clark Paul J, Thompson Alexander, Tillmann Hans L, McHutchison John G, Moseley M Arthur, McCarthy Jeanette J
Abstract excerpt
INTRODUCTION: Polymorphisms near the IL28B gene (e.g. rs12979860) encoding interferon λ3 have recently been associated with both spontaneous clearance and treatment response to pegIFN/RBV in chronic hepatitis C (CHC) patients. The molecular consequences of this genetic variation are unknown. To gain further insight into IL28B function we assessed the association of rs12979860 with expression of protein...
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