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Article

Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C.

Journal of gastroenterology - 1 Apr 2011

Chayama Kazuaki, Hayes C Nelson, Yoshioka Kentaro, Moriwaki Hisataka, Okanoue Takashi, Sakisaka Shotaro, Takehara Tetsuo, Oketani Makoto, Toyota Joji, Izumi Namiki, Hiasa Yoichi, Matsumoto Akihiro, Nomura Hideyuki, Seike Masataka, Ueno Yoshiyuki, Yotsuyanagi Hiroshi, Kumada Hiromitsu

Abstract excerpt

BACKGROUND: Treatment of genotype 1b chronic hepatitis C virus (HCV) infection has been improved by extending peg-interferon plus ribavirin combination therapy to 72 weeks, but predictive factors are needed to identify those patients who are likely to respond to long-term therapy. METHODS: We analyzed amino acid (aa) substitutions in the core protein and the interferon sensitivity determining region (ISDR) of...

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PMID: 21246384
DOI: 10.1007/s00535-010-0358-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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