Article
High predictive accuracy of an unbiased proteomic profile for sustained virologic response in chronic hepatitis C patients.
Hepatology (Baltimore, Md.) - 1 Jun 2011
Patel Keyur, Lucas Joseph E, Thompson J Will, Dubois Laura G, Tillmann Hans L, Thompson Alexander J, Uzarski Diane, Califf Robert M, Moseley Martin A, Ginsburg Geoffrey S, McHutchison John G, McCarthy Jeanette J
Abstract excerpt
UNLABELLED: Chronic hepatitis C (CHC) infection is a leading cause of endstage liver disease. Current standard-of-care (SOC) interferon-based therapy results in sustained virological response (SVR) in only one-half of patients, and is associated with significant side effects. Accurate host predictors of virologic response are needed to individualize treatment regimens. We applied a label-free liquid...
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