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Article

Prometastatic Molecular Profiles in Breast Tumors From Socially Isolated Women

1 Jul 2018

Abstract excerpt

BACKGROUND: Social isolation is associated with accelerated breast cancer progression and increased disease recurrence and mortality, but the underlying biological mechanisms remain poorly understood. In preclinical models, beta-adrenergic signaling from fight-or-flight stress responses can stimulate prometastatic processes in the tumor microenvironment including upregulation of M2 macrophages,...

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Identifiers

PMID: 30057973
DOI: 10.1093/jncics/pky029

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