Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chronic Social Isolation Is Associated with Metabolic Gene Expression Changes Specific to Mammary Adipose Tissue

18 Jun 2013

Abstract excerpt

Chronic social isolation is linked to increased mammary tumor growth in rodent models of breast cancer. In the C3(1)/SV40 T-antigen FVB/N (TAg) mouse model of "triple-negative" breast cancer, the heightened stress response elicited by social isolation has been associated with increased expression of metabolic genes in the mammary gland before invasive tumors develop (i.e., during the in situ carcinoma stage). To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Cancer Risks and Factors
Share to Nutrition, Genetics, and Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23780289
DOI: 10.1158/1940-6207.capr-12-0458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Chronic Social Isolation Is Associated with Metabolic Gene Expression Changes Specific to Mammary Adipose TissuePMID 23780289Read ↗

Prometastatic Molecular Profiles in Breast Tumors From Socially Isolated WomenSemantic proximity Read ↗

Thermoneutral Housing has Limited Effects on Social Isolation-Induced Bone Loss in Male C57BL/6J MiceSemantic proximity Read ↗

Susceptibility of Glucose Regulation to Social IsolationSemantic proximity Read ↗

Metabolic heterogeneity of activated beige/brite adipocytes in inguinal adipose tissue.Semantic proximity Read ↗

Single-Cell RNA-seq Reveals Obesity-Induced Alterations in the Brca1-Mutated Mammary Gland MicroenvironmentSemantic proximity Read ↗

Adipocyte mesenchymal transition contributes to mammary tumor progressionSemantic proximity Read ↗

Genetic background and diet affect brown adipose gene coexpression networks associated with metabolic phenotypes.Semantic proximity Read ↗

Annexin-A1 deficiency attenuates stress-induced tumor growth via fatty acid metabolism in mice: an Integrated multiple omics analysis on the stress- microbiome-metabolite-epigenetic-oncology (SMMEO) axisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.