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Genetic testing and clinical relevance of patients with thoracic aortic aneurysm and dissection in northwestern China.

Molecular genetics & genomic medicine - 1 Oct 2021

Li Jinjie, Yang Liu, Diao Yanjun, Zhou Lei, Xin Yijuan, Jiang Liqing, Li Rui, Wang Juan, Duan Weixun, Liu Jiayun

Abstract excerpt

BACKGROUND: Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening pathology that remains a challenge worldwide. Up to 40% of TAAD cases are hereditary with complex heterogeneous genetic backgrounds. The purposes of this study were to determine the diagnostic rate of patients with TAAD, investigate the molecular pathologic spectrum of TAAD by next-generation sequencing (NGS), and explore the future...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34498425
DOI: 10.1002/mgg3.1800
PMCID: PMC8580079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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