Article
A comparison of qPCR and ddPCR used for quantification of the JAK2 V617F allele burden in Ph negative MPNs.
Annals of hematology - 1 Dec 2018
Link-Lenczowska Dorota, Pallisgaard Niels, Cordua Sabrina, Zawada Magdalena, Czekalska Sylwia, Krochmalczyk Dorota, Kanduła Zuzanna, Sacha Tomasz
Abstract excerpt
Philadelphia-negative myeloproliferative neoplasms (MPNs) are a diverse group of diseases whose common feature is the presence of V617F mutation of the JAK2 gene. In the era of novel therapeutic strategies in MPNs, such as JAK-inhibitor therapy, there is a growing need for establishing high sensitive quantitative methods, which can be useful not only at diagnosis but also for monitoring therapeutic outcomes, such...
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