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Article

Transcriptome reveals the overexpression of a kallikrein gene cluster (KLK1/3/7/8/12) in the Tibetans with high altitude-associated polycythemia.

International journal of molecular medicine - 1 Feb 2017

Li Kang, Gesang Luobu, Dan Zeng, Gusang Lamu

Abstract excerpt

High altitude-associated polycythemia (HAPC) is a very common disease. However, it the disease is still unmanageable and the related molecular mechanisms remain largely unclear. In the present study, we aimed to explore the molecular mechanisms responsible for the development of HAPC using transcriptome analysis. Transcriptome analysis was conducted in 3 pairs of gastric mucosa tissues from patients with HAPC and...

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Source

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Identifiers

PMID: 28000848
DOI: 10.3892/ijmm.2016.2830
PMCID: PMC5358693

Genes

KLK1
KLK7
KLK12
KLK3
KLK8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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