Genetic polymorphism of the thrombospondin-related apical merozoite protein (TRAMP) of Plasmodium knowlesi in Malaysia.

doi:10.1007/s00436-022-07716-z

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Article

Genetic polymorphism of the thrombospondin-related apical merozoite protein (TRAMP) of Plasmodium knowlesi in Malaysia.

Parasitology research - 1 Jan 2023

Ng Yee Ling, Lau Yee Ling, Hamid Mohd Hafizi Abdul, Jelip Jenarun, Ooi Choo Huck, Mudin Rose Nani, Jaimin Joel Judson, Fong Mun Yik

Abstract excerpt

Plasmodium knowlesi is a simian malaria parasite that causes significant zoonotic infections in Southeast Asia, particularly in Malaysia. The Plasmodium thrombospondin-related apical merozoite protein (TRAMP) plays an essential role in the invasion of the parasite into its host erythrocyte. The present study investigated the genetic polymorphism and natural selection of the full length PkTRAMP from P. knowlesi...

Topics

Humans
Genetic Variation
Malaria
Malaysia
Merozoites
Plasmodium knowlesi
Polymorphism, Genetic
Protozoan Proteins

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Identifiers

PMID: 36378331
DOI: 10.1007/s00436-022-07716-z
PMCID: PMC9664425

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