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Article

Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity

27 Jul 2018

Abstract excerpt

Gliotoxin contributes to the virulence of the fungus Aspergillus fumigatus in non-neutropenic mice that are immunosuppressed with corticosteroids. To investigate how the absence of gliotoxin affects both the fungus and the host, we used a nanoString nCounter to analyze their transcriptional responses during pulmonary infection of a non-neutropenic host with a gliotoxin-deficient ΔgliP mutant. We found that the...

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PMID: 30052103
DOI: 10.1080/21505594.2018.1482182

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