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Article

A domain responsible for spontaneous conversion of bank vole prion protein.

Brain pathology (Zurich, Switzerland) - 1 Mar 2019

Kobayashi Atsushi, Matsuura Yuichi, Takeuchi Atsuko, Yamada Masahito, Miyoshi Ichiro, Mohri Shirou, Kitamoto Tetsuyuki

Abstract excerpt

Bank vole is a small rodent that shows high susceptibility to infection with diverse prion strains. To determine whether the increased susceptibility of bank voles to prion diseases can be attributed to the intrinsic nature of bank vole prion protein (PrP) or to host factors other than PrP, we produced transgenic mice overexpressing bank vole PrP. These transgenic mice spontaneously developed neurological illness...

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Identifiers

PMID: 30051525
DOI: 10.1111/bpa.12638
PMCID: PMC8028566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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