Article
Clinical potential of circulating tumour DNA in patients receiving anticancer immunotherapy.
Nature reviews. Clinical oncology - 1 Oct 2018
Cabel Luc, Proudhon Charlotte, Romano Emanuela, Girard Nicolas, Lantz Olivier, Stern Marc-Henri, Pierga Jean-Yves, Bidard François-Clément
Abstract excerpt
Considerable interest surrounds the use of immune-checkpoint inhibitors in patients with solid tumours following the demonstration of the impressive clinical efficacy of anti-programmed cell death protein 1 and anti-programmed cell death 1 ligand 1 antibodies in several tumour types. However, the emergence of unexpected tumour response patterns, such as pseudoprogression or hyperprogression, might complicate the...
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