Article
Circulating-tumor DNA as an early detection and diagnostic tool.
Current opinion in genetics & development - 1 Feb 2017
Butler Timothy M, Spellman Paul T, Gray Joe
Abstract excerpt
The development of new circulating-tumor DNA (ctDNA) analysis techniques has led to an explosion of studies demonstrating exciting clinical applications. Non-invasive genotyping can characterize mutations of interest without the need for an invasive biopsy. Serial ctDNA monitoring can assess response to treatment, and potentially identify mechanisms of resistance. Perhaps most excitingly, sensitive ctDNA analysis...
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