Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-214-3p in the Kidney Contributes to the Development of Hypertension.

Journal of the American Society of Nephrology : JASN - 1 Oct 2018

Liu Yong, Usa Kristie, Wang Feng, Liu Pengyuan, Geurts Aron M, Li Junhui, Williams Anna Marie, Regner Kevin R, Kong Yiwei, Liu Han, Nie Jing, Liang Mingyu

Abstract excerpt

BACKGROUND: In spite of extensive study, the mechanisms for salt sensitivity of BP in humans and rodent models remain poorly understood. Several microRNAs (miRNAs) have been associated with hypertension, but few have been shown to contribute to its development. METHODS: We examined miRNA expression profiles in human kidney biopsy samples and rat models using small RNA deep sequencing. To inhibit an miRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure
Share to Gene Knockout Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Kidney

Share to Nitric Oxide Synthase Type III

Share to Rats, Inbred Dahl

Share to Rats, Transgenic

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 30049682
DOI: 10.1681/ASN.2018020117
PMCID: PMC6171279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-214-3p in the Kidney Contributes to the Development of Hypertension.PMID 30049682Read ↗

Polymorphisms of microRNAs are associated with salt sensitivity in a Han Chinese population: the EpiSS study.Semantic proximity Read ↗

Gene Expression Profiling Reveals Renin mRNA Overexpression in Human Hypertensive Kidneys and a Role for MicroRNAsSemantic proximity Read ↗

Associations of microRNA Gene Polymorphisms With Salt Sensitivity, Longitudinal Blood Pressure Changes, and Hypertension Incidence in the Chinese Population.Semantic proximity Read ↗

Chromatin State Maps of Blood Pressure-Relevant Renal Segments Reveal Potential Regulatory Role for SNPs.Semantic proximity Read ↗

The emerging role of non-coding RNA in essential hypertension and blood pressure regulation.Semantic proximity Read ↗

Hypertension and chronic kidney disease: controversies in pathogenesis and treatment.Semantic proximity Read ↗

Tissue-specific effects of targeted mutation of Mir29b1 in rats.Semantic proximity Read ↗

Deficiency of MicroRNA-181a Results in Transcriptome-Wide Cell Specific Changes in the Kidney that Lead to Elevated Blood Pressure and Salt SensitivitySemantic proximity Read ↗

Kidney failure, arterial hypertension and left ventricular hypertrophy in rats with loss of function mutation of SOD3.Semantic proximity Read ↗

Resequencing Epithelial Sodium Channel Genes Identifies Rare Variants Associated With Blood Pressure Salt-Sensitivity: The GenSalt Study.Semantic proximity Read ↗

Effects of environmental and genetic risk factors for salt sensitivity on blood pressure in northern China: the systemic epidemiology of salt sensitivity (EpiSS) cohort studySemantic proximity Read ↗

Associations of corin genetic polymorphisms with salt sensitivity, blood pressure changes, and hypertension incidence in Chinese adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.