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The First Molecular Screening of MLH1 and MSH2 Genes in Moroccan Colorectal Cancer Patients Shows a Relatively High Mutational Prevalence.

Genetic testing and molecular biomarkers - 1 Aug 2018

Moufid Fatima Zahra, Bouguenouch Laila, El Bouchikhi Ihssane, Chbani Laila, Iraqui Houssaini Mohamed, Sekal Mohamed, Belhassan Khadija, Bennani Bahia, Ouldim Karim

Abstract excerpt

INTRODUCTION: Lynch syndrome (LS) is an autosomal dominant disorder characterized by early age of onset and increased risk of developing extracolonic tumors. Molecular diagnosis of LS requires identification of germline mutations in one of the Mismatch Repair (MMR) genes. AIM: The objective of the study was to investigate the prevalence of MLH1/MSH2 mutation carriers among Moroccan patients with colorectal cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30044143
DOI: 10.1089/gtmb.2018.0067

Genes

MLH1
MSH2
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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