Article
A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America.
BMC cancer - 5 Sept 2017
Rossi Benedito Mauro, Palmero Edenir Inêz, López-Kostner Francisco, Sarroca Carlos, Vaccaro Carlos Alberto, Spirandelli Florencia, Ashton-Prolla Patricia, Rodriguez Yenni, de Campos Reis Galvão Henrique, Reis Rui Manuel, Escremim de Paula André, Capochin Romagnolo Luis Gustavo, Alvarez Karin, Della Valle Adriana, Neffa Florencia, Kalfayan Pablo German, Spirandelli Enrique, Chialina Sergio, Gutiérrez Angulo Melva, Castro-Mujica Maria Del Carmen, Sanchez de Monte Julio, Quispe Richard, da Silva Sabrina Daniela, Rossi Norma Teresa, Barletta-Carrillo Claudia, Revollo Susana, Taborga Ximena, Morillas L Lena, Tubeuf Hélène, Monteiro-Santos Erika Maria, Piñero Tamara Alejandra, Dominguez-Barrera Constantino, Wernhoff Patrik, Martins Alexandra, Hovig Eivind, Møller Pål, Dominguez-Valentin Mev
Abstract excerpt
BACKGROUND: Genetic counselling and testing for Lynch syndrome (LS) have recently been introduced in several Latin America countries. We aimed to characterize the clinical, molecular and mismatch repair (MMR) variants spectrum of patients with suspected LS in Latin America. METHODS: Eleven LS hereditary cancer registries and 34 published LS databases were used to identify unrelated families that fulfilled the...
Topics
Join the communities discussing this publication.