Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis

24 Jul 2018

Abstract excerpt

BACKGROUND: The origin of collagen-producing cells in lung fibrosis is unclear. The involvement of embryonic signaling pathways has been acknowledged and trans-differentiation of epithelial cells is discussed critically. The work presented here investigates the role of TGFB in cytoskeleton remodeling and the expression of Epithelial-Mesenchymal-Transition markers by Alveolar Epithelial Cells Type II and tests the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective Tissue Growth Factor Research
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Neonatal Respiratory Health Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30041633
DOI: 10.1186/s12931-018-0841-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesisPMID 30041633Read ↗

Analysis of the TGFβ-induced program in primary airway epithelial cells shows essential role of NF-κB/RelA signaling network in type II epithelial mesenchymal transitionSemantic proximity Read ↗

Transcriptomic changes during TGF-β-mediated differentiation of airway fibroblasts to myofibroblastsSemantic proximity Read ↗

Alveolar epithelial cells are competent producers of interstitial extracellular matrix with disease relevant plasticity in a human in vitro 3D modelSemantic proximity Read ↗

TGFβ controls alveolar type 1 epithelial cell plasticity and alveolar matrisome gene transcriptionSemantic proximity Read ↗

TGF-β controls alveolar type 1 epithelial cell plasticity and alveolar matrisome gene transcription in miceSemantic proximity Read ↗

Bulk RNA-Sequencing of small airway cell cultures from IPF and post-COVID lung fibrosis patients illustrates disease signatures and differential responses to TGF- <i>β</i> 1 treatmentSemantic proximity Read ↗

Collagen 3D matrices as a model for the study of cell behavior in pulmonary fibrosisSemantic proximity Read ↗

Mechanisms and Therapeutic Potential of Myofibroblast Transformation in Pulmonary FibrosisSemantic proximity Read ↗

Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lungSemantic proximity Read ↗

TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT)Semantic proximity Read ↗

Recapitulating idiopathic pulmonary fibrosis related alveolar epithelial dysfunction in an iPSC-derived air-liquid interface modelSemantic proximity Read ↗

Idiopathic pulmonary fibrosis: Epithelial-mesenchymal interactions and emerging therapeutic targetsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.