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Article

Selection analyses of paired HIV-1 gag and gp41 sequences obtained before and after antiretroviral therapy.

Scientific data - 24 Jul 2018

Tzou Philip L, Rhee Soo-Yon, Pond Sergei L Kosakovsky, Manasa Justen, Shafer Robert W

Abstract excerpt

Most HIV-1-infected individuals with virological failure on a pharmacologically-boosted protease inhibitor (PI) regimen do not develop PI-resistance protease mutations. One proposed explanation is that HIV-1 gag or gp41 cytoplasmic domain mutations might also reduce PI susceptibility. In a recent study of paired gag and gp41 sequences from individuals with virological failure on a PI regimen, we did not identify...

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Share to Anti-HIV Agents
Share to gag Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp41

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Source

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Identifiers

PMID: 30040081
DOI: 10.1038/sdata.2018.147
PMCID: PMC6057438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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