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Article

Expanded Spectrum of Antiretroviral-Selected Mutations in Human Immunodeficiency Virus Type 2.

The Journal of infectious diseases - 11 Jun 2020

Tzou Philip L, Descamps Diane, Rhee Soo-Yon, Raugi Dana N, Charpentier Charlotte, Taveira Nuno, Smith Robert A, Soriano Vicente, de Mendoza Carmen, Holmes Susan P, Gottlieb Geoffrey S, Shafer Robert W

Abstract excerpt

BACKGROUND: HIV-1 and HIV-2 differ in their antiretroviral (ARV) susceptibilities and drug resistance mutations (DRMs). METHODS: We analyzed published HIV-2 pol sequences to identify HIV-2 treatment-selected mutations (TSMs). Mutation prevalences were determined by HIV-2 group and ARV status. Nonpolymorphic mutations were those in <1% of ARV-naive persons. TSMs were those associated with ARV therapy after...

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Identifiers

PMID: 31965175
DOI: 10.1093/infdis/jiaa026
PMCID: PMC7289557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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