Article
Poor Prognostic Implication of ASXL1 Mutations in Korean Patients With Chronic Myelomonocytic Leukemia.
Annals of laboratory medicine - 1 Nov 2018
Kim Hyun Young, Lee Ki O, Park Silvia, Jang Jun Ho, Jung Chul Won, Kim Sun Hee, Kim Hee Jin
Abstract excerpt
BACKGROUND: Molecular genetic abnormalities are observed in over 90% of chronic myelomonocytic leukemia (CMML) cases. Recently, several studies have demonstrated the negative prognostic impact of ASXL1 mutations in CMML patients. We evaluated the prognostic impact of ASXL1 mutations and compared five CMML prognostic models in Korean patients with CMML. METHODS: We analyzed data from 36 of 57 patients diagnosed as...
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